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Glossary
A-D
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J-O
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Adenocarcinoma
A type of cervical cancer developed from the mucus-producing gland cells of the endocervix. Adenocarcinomas originate from glands and make up about 10-20% of cervical cancers.
Adenosquamous Carcinomas (Mixed Carcinomas)
A term used when a cancer has characteristics of both squamous cell carcinomas and adenocarcinomas.
Adjuvant Chemotherapy
Chemotherapy used as an additional treatment in cases where the cancer is thought to be completely removed by a primary treatment, usually surgery, but statistically there is a chance of recurrence. Radiation and chemotherapy can be used as primary and/or adjuvant treatments depending on the condition, recommendation and personal decision made by the patient.
Advanced Breast Biopsy Instrument (ABBI)
A tool that can be used during a core needle biopsy. The ABBI uses a rotating circular knife to remove a larger cylinder of tissue for examination. The ABBI procedure removes more tissue than other types of biopsies and is performed using local anesthesia.
Ampulla (of the Fallopian Tube)
The second portion of the fallopian tube, which curves over the ovary. It is the most common site of human fertilization.
Anticancer Drugs
Drugs used to destroy or disable cancer cells.
Areola
The darker circle of skin around the nipple of the breast.
Arteries
Blood vessels that carry oxygen-rich blood from the heart to the different tissues of the body.
Atypical Hyperplasia
An increase in the number of cells causing some type of an enlargement or abnormality. Atypical hyperplasia can be related to inflammation, hormones, or cancer. Even if the condition is not cancer at the time of diagnosis, the diagnosis itself increases future risk for cancer.
Axillary Lymph Node Dissection
A surgical procedure involving the removal of lymph nodes from under the arm, referred to as the axilla. This procedure helps the provider determine the best course of treatment for the cancer based on the absence or presence of tumor cells in the lymph nodes. The procedure can be done at the same time as a mastectomy and during or after a lumpectomy.
Axillary Lymph Nodes
Lymph nodes found in the armpit region, referred to as the axilla, that drain lymph channels from the breast.
BRCA1
A gene that when mutated confers a high risk of hereditary breast and ovary cancer.
BRCA2
A gene that when mutated confers a high risk of hereditary breast and ovary cancer.
Barium Enema
A series of x-rays of the large intestine, to include the colon and rectum. An enema with a barium solution, a contrast medium, is given to visualize the intestine on the x-rays.
Benign
A condition that is noncancerous, meaning it does not invade surrounding tissue, and usually does not grow rapidly or spread to other organs. Benign conditions are often mild and not life threatening.
Biological Therapy
A type of cancer treatment that works with the body’s immune system. It can help fight cancer or help control side effects from other cancer treatments like chemotherapy.
Bilateral Salpingo-oophorectomy
A surgical procedure to remove both ovaries and the fallopian tubes. This procedure can be done laproscopically, or using an open abdominal or vaginal approach, and is frequently performed with the removal of the uterus (hysterectomy).
Biopsy
The removal of cells, tissue, or fluid to be inspected by a pathologist for absence or presence of cancer cells. This procedure can be performed in a variety of ways including incisional, excisional, core needle biopsy, or needle aspiration.
Bladder
The organ in the pelvis that stores urine produced by the kidneys until it is excreted via urination.
Breast(s)
The mammary gland, composed mostly of fatty tissue and a complex network of ducts and lobules, which produce milk in females during lactation.
Breast-Conserving Surgery (Breast-Sparing Surgery)
A procedure designed to remove breast cancer but not the entire breast. It is also called breast-sparing surgery, lumpectomy, segmental mastectomy, and partial mastectomy.
Breast Reconstruction
The rebuilding of the contour of the breast, along with the nipple and areola. There are two main types of reconstruction, including saline breast implants and muscle flap reconstruction. In saline implants, a tissue expander is placed beneath the skin and chest muscle to stretch the skin before the implants are inserted. Muscle flap reconstruction involves using tissue taken from the patient’s back, stomach or buttocks to rebuild the contour of the breast.
CA-125
An abbreviation for Cancer Antigen, a tumor marker that may be elevated in the blood of some people with specific types of cancers.
Calcifications
Tiny mineral deposits within the breast tissue that appear as small white spots on the films of a mammogram, categorized as microcalcifications or macrocalcifications.
Carcinoma
Refers to any cancer that begins in the skin or other tissues known as epithelial cells that line or cover internal organs. Carcinoma is a malignant condition.
Carcinoma in situ
Generally a precursor to carcinoma, characterized by its lack of invasiveness to the surrounding tissues and organs. “In situ” means “in place.”
Cervical Biopsy
A biopsy that involves the removal of tissue from the cervix to look for precancerous cells or cancer cells.
Cervical Cancer
A carcinoma most frequently related to the Human Papillomavirus. This condition is usually has no symptoms until its advanced stages, which is why early detection by Pap smear is vital to optimal outcomes.
Cervical Dysplasia
A precancerous abnormality of the cells found on the surface of the cervix. Dysplasia is detected by Pap smear and is most commonly associated with the following risk factors: early onset of sexual activity, multiple sex partners, HPV, cigarette smoking and HIV.
Cervical Intraepithelial Neoplasia (CIN)
Precancerous changes in the cervix.
Cervical Polyps
Small, soft growths that protrude from the mouth of the cervix. They are very common and occur most often during pregnancy as a result of hormonal changes.
Cervicitis
An inflammation of the cervix usually caused by infection. Cervicitis can also be caused by chemical irritation; devices such as a pessary or diaphragm, or an allergy to spermicide or latex; and STDs and bacteria.
Cervix
The narrow, lower portion of the uterus.
Chemotherapy
A single drug or a combination of drugs used to treat cancer. These drugs are designed to destroy cancer cells; however, chemotherapy also damages healthy cells, causing a variety of side effects.
Chest X-ray
An x-ray taken of the thorax to visualize structures for abnormalities.
Chlamydia
A common sexually transmitted disease (STD) that can lead to pelvic inflammatory disease (PID), infertility, or urinary tract infection (UTI) if left untreated.
Chocolate Cyst
An endometrioma that is filled with dark, reddish-brown blood.
Cilia
Slender, microscopic, hair-like structures or organelles that extend from the surface of nearly all cells in the human body. In the fallopian tube, the cilia pulsate to move the egg from the ovary, through the fallopian tube, and into the uterus.
Core Needle Biopsy (CNB)
A procedure using a hollow needle to extract a sample of a lump or other suspicious tissue for examination.
Colonoscopy
An exam where a long, lighted tube is inserted into the rectum and colon. It may provide a visual diagnosis and opportunity for removal of suspect lesions.
Colorectal Cancer
A disease in which cancerous growths (tumors) are found in the tissues of the colon and/or rectum. Colorectal cancer can develop from precancerous polyps.
Colposcopy
A diagnostic exam using a device called a colposcope to examine the cervix, vagina, and vulva. The colposcope combines a bright light with a magnifying lens to enhance the visibility of suspicious or abnormal tissues that are usually biopsied at the time of the exam.
Computerized Tomography Scans (CT Scan)
A diagnostic imaging test that uses computers to create three-dimensional or cross-sectional images from a large series of two-dimensional x-ray images. CT Scans may be performed with or without oral or intravenous contrast dye to enhance visualization.
Conization
Also known as a cone biopsy, conization involves the surgical removal of a cone-shaped sample of tissue from the cervix for diagnostic or therapeutic purposes.
Corpus Luteum
The result of the rupture of an ovarian follicle during the luteal stage of the menstrual cycle; a collection of blood due to rupture.
Cryocautery (Cryosurgery)
The freezing of the cervix to treat abnormal tissue.
Curette
A spoon-shaped instrument.
Cyst
A sac or capsule in the body. It may be filled with fluid, gaseous, or semisolid material.
Cystadenomas
Cysts that develop from cells on the outer surface of the ovary.
Cystectomy
Removal of a cyst; also the medical term for surgical removal of all or part of the urinary bladder.
Cystitis
An infection of the bladder.
Cystometry
A test that measures pressure in your bladder and in the surrounding region during bladder filling.
Cystosarcoma Phyllodes
Both benign and malignant phyllodes tumors.
Cystoscopy
A procedure that uses a tube-like instrument to look inside the urethra and bladder.
Debulking Surgery
The surgical removal of as much of a malignant tumor as possible when it cannot be completely removed.
Dermoid Cysts
Cysts that are made up of different kinds of tissue from other parts of the body, such as skin, hair, fat, and teeth.
Diagnostic Mammograms
A mammogram performed to evaluate the breast due to symptoms. In most cases, the diagnostic mammogram provides standard views of the breast as well as supplemental views in relation to the complaint or symptoms. The diagnostic films are frequently viewed prior to the patient departing the office to discuss outcomes and potential procedures and/or treatments if indicated.
Diethylstilbestrol (DES)
The earliest synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971 to prevent miscarriages. In women that have taken DES, there may be an increased risk of uterine, ovarian, or breast cancer. In daughters of women who have taken DES during their pregnancy, there is an increased risk of clear cell carcinoma of the vagina or cervix.
Dilation and Curettage (D&C)
A procedure to remove tissue from the cervical canal or the inner lining of the uterus. The cervix is dilated (made larger) and a curette (spoon-shaped instrument) is inserted into the uterus to remove tissue. This procedure is usually performed to obtain tissue samples, to stop prolonged bleeding, to remove small tumors, or to remove fragments of placenta after a miscarriage.
Duct Ectasia
Widening of the ducts of the breast that is often related to breast inflammation. This is a benign condition characterized by nipple discharge, swelling, retraction of the nipple, or a lump that can be felt.
Ductal Carcinoma in Situ (DCIS)
A form of breast pre-cancer in which carcinoma, or abnormal cells, are found in the lining of a breast duct. “In situ” means that the abnormal cells have not spread outside of the duct to other tissues in the breast.
Ductal System
The network of lobules that produce milk and ducts that carry the milk through ductal branches to the nipple. Each breast normally has on average five to 10 ductal systems.
Ductogram
A diagnostic test where contrast dye is injected into a specific duct through a small needle or catheter, which allows the provider an enhanced view of the ducts via x-ray.
Ducts
The tubes that transport milk to the nipple during feeding and link the lobes together.
Dysmenorrhea
Menstrual cramps that occur just before and during a woman’s period.
Dysplasia
An abnormal development of cells or tissues. This is a precancerous condition that may or may not develop into cancer.
Ectocervix
The part of the cervix closest to the vagina.
Ectopic Pregnancy
A potentially life-threatening condition in which a pregnancy occurs outside the uterus, most often in the fallopian tube.
Endocervical Curettage
A technique for obtaining a biopsy of the cervix where the provider uses a small, spoon-shaped instrument called a curette, or a soft, thin brush to scrape a small sample of tissue from the cervical canal.
Endocervix
The part of the cervix closest to the body.
Endometrial Cancer
A type of uterine cancer, which starts in the cells lining the uterus.
Endometrial Hyperplasia
A condition that occurs when the lining of the uterus, called the endometrium, thickens from increased production of endometrial cells. Despite being a benign condition it is a significant risk factor for the development of endometrial cancer.
Endometrioma
A cyst that forms when endometrial tissue grows outside of the uterus; frequently found in the ovaries or on the perineum, which is the tissue between the uterus and rectum. An endometrioma is also known as a "chocolate cyst" because it is filled with dark, reddish-brown blood.
Endometriosis
A condition where the tissue that normally lines the uterus grows in other areas of the body. This may cause pain, irregular bleeding, and infertility.
Endometrium
The inner lining of the uterus.
Excisional Biopsy
A surgical biopsy used to remove an entire lesion or suspicious area as well as some surrounding tissue.
Estrogen
A female hormone, produced mostly in the ovaries. It is essential for the healthy development and functioning of the female reproductive system, in keeping bones strong, and brain cells healthy.
External Radiation Therapy
Outpatient treatments providing external beam radiation locally directed from a machine aimed toward the affected area or organ to treat cancer.
Fallopian Tubes
The fallopian tube transports the egg from the ovary to the uterus. There are two fallopian tubes, one connecting to each ovary. Fertilization (joining of female egg with male sperm) usually takes place within the fallopian tubes.
Fibroadenomas
Benign tumors made up of both glandular breast tissue and supporting, or stromal, tissue.
Fibrocystic
Refers to the fact that both fibrosis and cysts are often present in the breast.
Fibrocystic Changes
A benign condition, fibrocystic changes are characterized by breast tenderness, pain, lumps, burning, and at times itching. These changes may occur in relationship to normal hormonal changes and the menstrual cycle.
Fibromyoma (Uterine Fibroid)
Benign growths of the uterus formed from a mix of muscle and fibrous tissues; also known as uterine fibroid.
Fimbriae
Fingerlike projections at the end of the fallopian tube that are connected to the ovary and produce a peritoneal fluid in which the egg is transported.
Fine Needle Aspiration Biopsy (FNAB)
A test that uses a thin needle to remove fluid or a small amount of tissue from a lump or abnormal area of the affected site.
Functional Ovarian Cyst
An ovarian cyst that develops from tissue that changes in the normal process of ovulation. There are two types of functional cysts: follicular and corpus luteal cysts.
Fundus
The dome-shaped top of the uterus.
Glandular Tissue
Tissue that produces or secretes a substance and comprises a gland; any tissue that is made from gland cells.
Gonorrhea
A common sexually transmitted disease (STD) that can lead to pelvic inflammatory disease (PID) if left untreated.
Granular Cell Tumors
A tumor rarely found in the breast that is approximately ½ to 1 inch across, and feels like a firm, movable lump. Granular cell tumors are more frequently found on extremities, trunk, head and neck, but can be found anywhere.
Hodgkin's Lymphoma
Hodgkin's lymphoma is a malignancy (cancer) of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow.
Hormone Replacement Therapy (HRT)
A system of medical treatment involving the administration of a series of drugs to artificially boost hormone levels or act as a replacement for the hormone.
Hormone Therapy
Involves administering medications designed to inhibit the growth of cancer cells by blocking the hormones that the cells need to grow.
Hormone Receptors
Proteins that hormones can attach to. A hormone receptor test measures the amount of certain proteins in cancer tissue. A high level of hormone receptors may mean that hormones help the cancer grow.
Human Papillomavirus (HPV)
HPV is a group of viruses that includes more than 150 different strains or types. Many of these strains are sexually transmitted, and they can infect the genital area of both men and women.
Hysterectomy
Surgery to remove both the cervix and the uterus.
Hysteroscope
A device used to remove uterine polyps.
In situ
Refers to the stage in which abnormal cells have not spread or invaded other tissues.
Infertility
The inability to become pregnant after a year of trying and/or the inability to carry a pregnancy to term.
Inflammatory Breast Cancer
Also classified as Stage III breast cancer, this is where the cancer has spread to the breast skin, causing swelling and redness.
Internal Radiation Therapy
A form of therapy in which a radiation source is placed inside the body.
Intraductal Papillomas
Unusual growths of gland tissue, fibrous tissue, and blood vessels. These small tumors are often found in the large milk ducts near the nipple and can cause bloody discharge from the nipple. Intraductal papillomas are also found in small ducts in areas of the breast further from the nipple.
Intraperitoneal Chemotherapy
A procedure in which drugs are given directly into the abdomen and pelvis through a thin tube. The drugs destroy or control cancer in the abdomen and pelvis. This form of treatment is rarely used.
Invasive Ductal Carcinoma (IDC)
Breast cancer that begins in the ducts.
Invasive Lobular Carcinoma (ILC)
Breast cancer that begins in the lobules.
Kidneys
Two bean-shaped organs that are part of the urinary system. The kidneys filter blood and send waste on as urine through the ureters to the bladder.
Laparoscopy
Also known as minimally invasive surgery, this is a surgical technique in which operations are performed through small incisions. Tiny cameras are inserted through the incision and used to transmit images to a video monitor.
Laparotomy
A procedure where tissue and fluid are removed from the pelvis and abdomen.
Laser Surgery
A procedure used to vaporize abnormal tissues.
Leiomyomas (Uterine Fibroids)
Uterine fibroids, also called fibromyomas or myomas.
Lesions
An abnormal change in the structure of an organ or body part due to an injury or disease.
Lobes
Each breast contains 15 to 20 lobes in a circular pattern. The amount of fat covering the lobes determines the size of the breast. Each lobe is made up of lobules.
Lobular Carcinoma in Situ (LCIS)
A benign, abnormal growth of cells in the lobules of the breast. “In situ” refers to the fact that the growth has not spread beyond the site of origin.
Lobules
Glands located in the breast where milk is produced before and after childbirth.
Local Therapy
Therapy designed to treat a specific locality or area of the body. For example, surgery and local radiation therapy are used to treat breast cancer, to remove or destroy the cancer in the breast.
Locally Advanced Breast Cancer
Cancer that has spread to large parts of the breast or the nearby lymph nodes but not to distant organs.
Loop Electrosurgical Excision Procedure (LEEP)
A biopsy where the provider uses an electric wire loop to slice off a thin, round piece of tissue.
Lump
An irregularly shaped mass or piece of tissue.
Lumpectomy
A surgery to remove only the part of the breast containing the tumor (the "lump") and some of the normal tissue that surrounds it.
Lymph Nodes
Bean-shaped structures scattered along vessels of the lymphatic system. Lymph nodes remove cell waste and fluids from the lymphatic system and help fight infections.
Lymphatic System
The system of lymph nodes and the vessels that connect them. Lymph nodes are located throughout the body, filtering out dangerous substances and producing infection-fighting cells called lymphocytes.
Lymphedema
A condition where fluid builds up in the arm and hand and causes swelling. Lymphedema often occurs after the removal of the lymph nodes.
Macrocalcifications
Large calcium deposits found in the breasts caused by aging of the breast arteries, past injuries, or inflammation. They generally are associated with benign conditions and usually do not require a biopsy.
Macrocysts
Large cysts.
Magnetic Resonance Imaging (MRI)
A test that uses a powerful magnet linked to a computer to make detailed pictures. Providers can view these pictures on a monitor or print them on film.
Malignant
Cancer that tends to invade and destroy nearby tissue and possibly spread (metastasize) to other parts of the body.
Malignant Germ Cell Tumor
Cancer that starts in a woman’s egg cells or a man’s sperm cells.
Mammary Ducts
Ducts that drain the lobes of the mammary gland at the nipple.
Mammography (Mammogram)
A screening or diagnostic exam conducted using low dose x-ray and compressing breast tissue to evaluate for tissue abnormalities such as cysts, tumors or calcifications.
Mammotome
Also known as a vacuum-assisted biopsy. During this procedure, a provider inserts a tube into the breast tissue and then uses suction to draw a cylinder of breast tissue into the tube. At the same time, a small rotating knife cuts and removes the tissue for examination. The needle is inserted only once and rotates to get the needed cores.
Margin
A small amount of healthy surrounding tissue.
Masses
Tumors or abnormal growth of tissue that can be either malignant or benign.
Mastitis
An inflammation of the mammary gland usually caused by infection. Mastitis often affects women who are breast-feeding or those who have had a break or crack in the skin.
Medical Oncologist
A physician who specializes in diagnosing and treating cancer using chemotherapy, hormonal therapy, and biological therapy.
Menopause
A term commonly used to refer to the period ending the female reproductive phase of life; the end of menstruation.
Menstrual Cycle
The cycle of menstruation and ovulation that occurs every 21 to 35 days. The cycle begins on the first day of menstruation.
Menstruation
The part of a woman’s menstrual cycle when the uterine lining is shed; also known as a period.
Metastasis
When cancer cells have broken away from the primary tumor and spread to other organs in the body through the blood stream or the lymphatic system.
Metastatic Cancer
A cancer that has spread (metastasized) from its original site to another area of the body.
Microcalcifications
Smaller deposits of calcium in the breast that may appear alone or in clusters.
Microcysts
Fluid that builds up inside the glands of the breast, initially forming small cysts that are detectable only when breast tissue is examined under a microscope.
Mittelschmerz
A German term for “middle pain,” mittelschmerz is pelvic pain on one side during ovulation, 12 to 16 days before menstruation. It can last a few minutes, a few hours, or a day or two.
Modified Radical Mastectomy
A type of surgical treatment for breast cancer. Using this technique, the surgeon removes the whole breast, and most or all of the lymph nodes under the arm. Often, the lining over the chest muscles is also removed. Other small chest muscles are sometimes removed to allow for easier access to the lymph nodes.
Mycoplasma
A type of bacteria associated with some sexually transmitted infections (STIs). Mycoplasma can cause urinary tract infection (UTI) if left untreated.
Myomas (Uterine Fibroids)
Benign growths or tumors of the uterus that often appear during childbearing years.
Myometrium
The outer layer of muscle tissue of the uterus.
Neoadjuvant Chemotherapy
A process where chemotherapy may be used before surgery in women with larger tumors.
Nerves
Fibers containing nerve cells that conduct electrical impulses (messages) from the brain and spinal cord to all other parts of the body.
Nocturia
Waking two or more times in the night to urinate.
Omentum
The thin, fatty pad of tissue that covers the intestines.
Oncology
The study of the diagnosis and treatment of cancer.
Ova
A female egg.
Ovarian Biopsy
A surgical procedure to determine if an ovarian mass is cancerous by removing and testing a tissue sample.
Ovarian Cancer
A cancer that develops in a woman’s ovaries. There are three main types of ovarian cancers: ovarian epithelial carcinomas, malignant germ cell tumors, and stromal cell carcinomas.
Ovarian Cysts
A collection of fluid surrounded by a thin wall within the ovaries. Cysts can vary in size and are usually benign.
Ovarian Epithelial Carcinomas
Ovarian cancer that begins in the cells on the surface of the ovary.
Ovarian Follicle
A cavity in the ovary that contains a developing egg surrounded by a covering of cells.
Ovarian Torsion (Adnexal Torsion)
Occurs when an ovary becomes twisted.
Ovarian Tumor
An abnormal growth of tissue in or on an ovary.
Ovaries
The part of the female reproductive system that produces eggs (ova) and that manufactures female hormones. The ovaries are located in the pelvis. Each ovary is similar in size and shape to an almond.
Overactive Bladder Syndrome
A problem with the bladder’s ability to store that causes sudden, frequent urges to urinate, nocturia, and/or urgency incontinence.
Ovulation
The process in the menstrual cycle when a mature ovarian follicle discharges an egg for reproduction.
Pap Smear (Pap Test)
A Papanicolaou (Pap) smear or test is a screening test to detect cervical cancer or other cervical disease and conditions. Cells are taken from the cervix and examined under a microscope to identify abnormalities.
Partial Mastectomy
Also called segmental mastectomy. This procedure involves the removal of the cancer, the breast tissue around the tumor, and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also removed.
Pectoralis
A large muscle located between the breast and the rib cage.
Pedunculated Uterine Fibroid
A fibroid that hangs by a stalk inside or outside the uterus.
Pelvic Exam
An exam during which a provider examines a woman’s vagina, uterus, ovaries, bladder, and rectum. In order to examine the upper part of the vagina and the cervix, the provider opens the vagina using a device called a speculum. This allows for a visual inspection and provides the opportunity to perform additional tests, such as cultures or Pap tests. During the pelvic exam, the provider will feel the uterus, checking for any lumps or changes in its size or shape.
Pelvic Inflammatory Disease (PID)
When bacteria from a sexually transmitted disease (STD) move upward from a woman’s vagina or cervix into her uterus, fallopian tubes, and ovaries.
Pelvic Ultrasound
A test that uses sound waves to create an image of the organs of the pelvis.
Pelvis
Bone structure formed by the bones of the hips and lower part of the spine. The pelvis is a bowl-shaped ring of bone that connects the legs to the spine and protects reproductive and digestive organs.
Pessary
A supportive device that can be used to treat uterine prolapse. This device is inserted into the vagina to hold the uterus in place.
Phyllodes Tumors
These tumors develop from the tissues between the lobules of the breast, also known as the intralobular stroma.
Polycystic Ovarian Syndrome (PCOS)
Characterized by ovaries that are two to five times larger than normal ovaries, polycystic ovaries usually have a white, thick, tough outer covering.
Postmenopausal
After menopause.
Premenopausal
Before menopause.
Post-void Residual (PVR)
A test that measures the amount of urine left after you urinate.
Progesterone
A female sex hormone that is released by the ovaries during every menstrual cycle to prepare the uterus for pregnancy and the breasts for milk production (lactation).
Progestin
The artificial form of progesterone that can be taken by mouth or injection as a hormonal supplement.
Prolactin
A pituitary hormone that stimulates the secretion of breast milk.
Prolapse
A condition that occurs when a part of the body slips from its normal position.
Prosthesis
An artificial device to replace or augment a missing or impaired part of the body. A breast form is an example of prosthesis.
Punch Biopsy
A procedure where a provider uses a sharp, hollow device to pinch off small samples of vulvar tissue for testing.
Pyelonephritis
An infection of the kidneys.
Radiation Oncologist
A physician who specializes in the use of radiation to treat cancerous or non-cancerous tumors.
Radiation Therapy
A treatment that uses targeted, high-energy rays to kill cancer cells. It affects cancer cells only in the treated area.
Radionuclide Scan
An imaging technique that uses small amounts of injected radioactive chemicals to provide information about kidney function.
Rectum
The last six to eight inches of the large intestine, which stores solid waste from the colon until it is expelled from the body through the anus.
Recurrent UTIs
Urinary tract infections that recur three or more times within a year or twice in six months.
Risk Factor
Something that increases a person's chance of developing a disease.
Scleroderma
An autoimmune disease in which the skin thickens and hardens; sometimes other parts of the body are affected and joint pain may result.
Screening Mammograms
A screening mammogram is an x-ray of the breast used to detect breast changes in women who have no signs or symptoms of breast cancer.
Segmental Mastectomy
A surgical procedure for the removal of breast cancer, as well as some of the breast tissue around the cancer and the lining over the chest muscles below the cancer. Usually some of the lymph nodes under the arm are also removed. A segmental mastectomy is sometimes called partial mastectomy.
Self-examination
An exam regularly performed by a woman of her breasts to check for lumps or other changes.
Sentinel Lymph Node Biopsy
A type of biopsy used to check for cancer cells in the lymph nodes. This technique uses dye and a radioactive marker to identify the lymph nodes at highest risk for containing metastatic cells.
Sexually Transmitted Disease (Sexually Transmitted Infection)
A disease or infection that is primarily passed from one person to another through sexual contact with the penis, vagina, rectum, or mouth.
Sigmoidoscopy
A diagnostic procedure that uses a flexible viewing tube to allow the provider to view the inner walls of the colon. During this procedure, a tube is gently passed into the colon through the anus.
Sonogram
Also known as an ultrasound, this is an imaging technique that uses high-frequency sound waves.
Sphincter
A ring of muscle surrounding and serving to guard or close an opening of an organ, such as the bladder.
Stages
Refers to how far a disease or cancer has progressed.
Stereotactic Biopsy
A computerized mammography machine that uses intersecting coordinates to pinpoint the lump or area of tissue abnormality. The tissue is removed and examined under a microscope.
Stress Incontinence
A condition in which the bladder leaks urine during physical activity or exertion.
Stromal Cell Carcinoma
A type of ovarian cancer that starts in the supporting (stromal) cells of the ovary.
Stromal Tissues
The connective tissue of an organ, gland, or other structure, as distinguished from the tissues performing the special function of the organ or part.
Squamous Cell Carcinoma
A type of cervical cancer that most often begins where the ectocervix joins the endocervix.
Squamous Intraepithelial Lesion (SIL)
Precancerous changes in the cervix.
Submucosal Fibroids
Fibroids that grow into the inner cavity of the uterus.
Subserosal Fibroids
Fibroids that project to the outside of the uterus.
Systemic Chemotherapy
A type of chemotherapy that is taken by mouth or injected into a vein. The drugs enter the bloodstream and destroy or control cancer throughout the body.
Systemic Lupus
An autoimmune disease that can involve the organs and joints.
Systemic Therapy
Treatment that affects the entire body, rather than a localized area. Types of systemic therapy include chemotherapy, hormone therapy, and biological therapy.
Tamoxifen
An anticancer drug that blocks the effects of estrogen on many organs, such as the breast. Estrogen promotes the growth of some breast and uterine cancers. Recent research suggests that tamoxifen may lower the risk of breast cancer in women with certain risk factors.
Targeted Therapy
The use of special drugs and other substances to attack specific molecular features or pathways involved in the development of cancer. Unlike chemotherapy drugs, targeted therapies can destroy cancer cells with minimal damage to the surrounding healthy cells.
Transvaginal Ultrasound
An ultrasound test during which the provider inserts a special wand into the vagina. This instrument emits high frequency sound waves aimed at the uterus. The sound waves bounce back to the wand and are used to form a picture that helps the provider identify abnormalities in the uterus.
Traumatic Fat Necrosis
A condition in which painless, round, firm lumps caused by damaged and disintegrating fatty tissues form in the breast. This is usually the result of injury to the breast. Necrosis can sometimes occur after surgery or radiation therapy, as a result of the body trying to repair the damage to the breast by forming scar tissue.
Tubal Ligation
A surgical procedure that closes a woman’s fallopian tubes. It’s often referred to as having your “tubes tied.”
Tubo-ovarian Abscess (TOA)
A serious complication of pelvic inflammatory disease (PID). A TOA is a collection of bacteria, pus, and fluid that builds up in the fallopian tube or ovary.
Tumor
A mass or lump of tissue made of abnormal cells that may eventually spread, or metastasize.
Ultrasound
Also known as a sonogram, an ultrasound is an imaging technique that uses high-frequency sound waves to visualize structures inside the body. Ultrasound imaging allows providers and patients to get an inside view of soft tissues and body cavities, without using invasive techniques.
Ureters
Two tubes that carry urine from the kidneys to the bladder.
Urethra
The tube that carries urine from the bladder out of the body. In women, the urethra is short and located just above the vagina.
Urethritis
An inflammation of the urethra.
Urge Incontinence
Involuntary urine leakage that immediately follows the urge to urinate.
Urinalysis
Testing done on a urine sample to check for the presence of bacteria, white blood cells, or other substances.
Urinary System (Urinary Tract)
A system in the human body that controls urination; includes the kidneys, ureters, bladder, and urethra.
Urinary Tract Infection (UTI)
An infection of any part or parts of the urinary system, which includes the urethra, the bladder, the ureters, and the kidneys.
Urodynamic Testing
Any procedure that examines how well the bladder, sphincters, and urethra are storing and releasing urine.
Uroflowmeter
A device that measures the volume and speed of urination.
Uterus
Part of a woman's reproductive system. It is a hollow, pear-shaped organ where a baby grows during pregnancy. The uterus is positioned in the pelvis between the bladder and the rectum.
Uterine Cancer
The most common cancer of the female pelvic reproductive system. Uterine cancer forms in the tissues of the uterus. Two types of uterine cancer are endometrial cancer and uterine sarcoma.
Uterine Fibroids
Benign growths of the uterus that often appear during childbearing years. Uterine fibroids are also called fibromyomas, leiomyomas or myomas, and are not usually associated with an increased risk of uterine cancer.
Uterine Polyps
Areas in the uterus where the lining, also called the endometrium, becomes overgrown and forms a mass referred to as a polyp. Uterine polyps can range in size from as small as a pinhead to the size of a golf ball or even larger.
Uterine Prolapse
The condition where the uterus has dropped from its position within the pelvis into the vagina. Normally, the uterus is held in place by the muscles and ligaments that make up the pelvic floor. Uterine prolapse results when pelvic floor muscles and ligaments weaken, providing inadequate support for the uterus. The uterus then descends into the vaginal canal.
Uterine Sarcoma
A rare cancer that begins in muscle or other tissues in the uterus.
Vacuum-Assisted Biopsy
Also called a Mammotome biopsy. During this procedure, a surgeon inserts a tube larger than those used in a typical core needle biopsy into the breast tissue. The provider then uses suction to draw a cylinder of breast tissue into the tube, and a small rotating knife cuts and removes the tissue for examination. The needle is inserted only once and rotates to get the needed cores.
Vagina
The muscular canal extending from the uterus to the exterior of the body. Also known as the birth canal.
Vein
A blood vessel that carries blood toward the heart.
Virilization
Development of male sex characteristics in a female.
Voiding Cystourethrogram
An x-ray image of the bladder and urethra taken while the bladder is full and during urination, or voiding.
Watchful Waiting
A passive technique used to determine whether cancer is growing slowly and not causing symptoms. The patient and the provider will carefully monitor the condition with regular physical exams and tests.
Wire Localization
A procedure used during a breast biopsy to help locate the lump or area of interest, especially if the lump is too small to locate by touch. After numbing the area with local anesthesia, a thin hollow needle is placed into the breast and x-ray pictures are taken to guide the needle to the suspicious area. A thin wire is placed through the center of the needle. A small hook at the end of the wire keeps it in place. The hollow needle is then removed and the surgeon uses the wire as a guide to locate the abnormal area to be removed.
Breast Diseases
The Breast
Risk Factors and Symptoms
Risk Factors
Chances of Developing Breast Cancer
Symptoms
Diagnosis and Tests
Self-Examination
Mammography
Other Imaging Tests
Real Patient – Breast Biopsy #1
Biopsy
Real Patient – Breast Biopsy #2
Benign Breast Conditions
Fibrocystic Changes
Fibroadenomas
Intraductal Papillomas
Traumatic Fat Necrosis
Mastitis
Lobular Carcinoma in Situ
Other Benign Conditions
Types of Breast Cancer
Real Patient – Breast Cancer
Ductal Carcinoma in Situ (DCIS) (Pre-Cancer)
Invasive Ductal Carcinoma
Invasive Lobular Carcinoma
Stages of Breast Cancer
Treatment
Surgery
Radiation
Chemotherapy
Hormone Therapy
Targeted Therapy
Side Effects
Living and Managing
Life After Treatment
Health and Emotional Concerns
Body Changes
Changes in Sex Life
Fertility
Uterine Diseases
The Uterus
Abnormal Uterine Bleeding (PALM-COEIN)
Real Patient – Heavy Bleeding and Hysterectomy
Ovulatory Dysfunction
Real Patient – Uterine Fibroid and Hysterectomy #1
Uterine Fibroids
Real Patient – Uterine Fibroid and Hysterectomy #2
Uterine Polyps
Endometrial Hyperplasia
Uterine Prolapse
Real Patient – Uterine Prolapse
Symptoms
Stages
Treatment
Uterine Cancer
Risk Factors
Symptoms
Diagnosis and Stages
Treatment
Cervical Diseases
Precancerous Cervical Diseases
Human Papillomavirus
Cervical Dysplasia
Real Patient – Cervical Dysplasia
Cervical Polyps
Cervicitis
The Cervix
Cervical Cancer
Risk Factors
Symptoms
Diagnosis
Pap Test
Colposcopy
Cervical Biopsy
Additional Tests
Stages of Cervical Cancer
Treatment
Surgery
Chemotherapy
Radiation Therapy
Follow-up Care
Real Patient – Imperforate Hymen
Fallopian Tube Diseases
The Fallopian Tubes
STDs and Tubo-ovarian Abscesses
Ectopic Pregnancy
Infertility
Real Patient - Infertility
Ovarian Diseases
The Ovaries
Benign Ovarian Diseases
Real Patient - Ovarian Cysts and Endometriosis
Ovarian Cysts
Ovarian Tumors
Polycystic Ovarian Syndrome (PCOS)
Pelvic Pain (with/without Endometriosis)
Real Patient – Pelvic Pain
Ovarian Torsion
Menopause
Ovarian Cancer
Risk Factors
Symptoms
Diagnosis
Blood Tests
Ultrasounds
Staging Surgery
Additional Tests
Stages of Ovarian Cancer
Treatment
Surgery
Chemotherapy
Radiation Therapy
Follow-up Care
Bladder Diseases
The Bladder and Urethra
Recurrent UTIs
Diagnosis
Treatment
Stress Incontinence
Diagnosis
Treatment
Overactive Bladder Syndrome
Diagnosis
Treatment
Resources
Atlas
FAQs
Glossary
Credits